Duke University
Medical Center
919 684-7755
Medical Center
919 684-7755
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Journal club Info: 919 684-7758 |
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Duke Center for In Vivo Microscopy (CIVM) is an NIH/NCRR National Biomedical Technology Research Center that develops medical technologies with applications for small animal imaging at microscopic resolution.
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We offer 2T, 7T, and 9.4T MR microscopy, micro-CT, micro x-ray, ultrasound, and optical imaging technologies. For details about our imaging facilities, CLICK HERE. To initiate a project with the Center, CLICK HERE to go to our collaboration link.
CIVM continues to expand our range of technical capabilities and applications, such as these examples:
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3He MR lung imaging
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4D micro-CT of the mouse heart
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4D heart analysis
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more about this research
press release about this research |
more about this image
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 2 positions available |
Assistant Professor | Post-doctoral Associate |
| e-mail for more information or call 919 684-7758 |
2009 department publications
| A Badea, RW Williams, GA Johnson, Genetic dissection of the mouse brain using high-field magnetic resonance microscopy, Neuroimage. 2009 May 1; 45(4):1067-1079, http://dx.doi.org/10.1016/j.neuroimage.2009.01.021. | A Mackenzie-Graham SK Tiwari-Woodruff, G Sharma, C Aguilar, KT Vo, LV Strickland, L Morales, B Fubara, M Martin, RE Jacobs, GA Johnson, et al., Purkinje cell loss in experimental autoimmune encephalomyelitis, NeuroImage, 48(4): 637-652, 2009 | |
| A Badea, GA Johnson, R Williams, Genetic dissection of the mouse CNS using magnetic resonance microscopy, invited paper: Current Opinion in Neurology 22:379–386, 2009 | SE Parnell, SK O’Leary Moore, EA Godin, DB Dehart, BW Johnson, GA Johnson, et al, MR microscopy defines ethanol-induced brain abnormalities in prenatal mice, Clinical and Experimental Research 33(4): 1001-1011, 2009 | |
| M Hyeok Bae, R Pan, T Wu, A Badea, Automated segmentation of mouse brain images using extended MRF, Neuroimage 46(3): 717-725, 2009 | E Samei, RS Saunders, CT Badea, KB Ghaghada, LW Hedlund, Y Qi, et al., Micro-CT imaging of breast tumors in rodents using a liposomal, nanoparticle contrast agent, International Journal of Nanomedicine 4: 277–282, 2009. | |
| K Frinkley Bing, GP Howles, Y Qi, et al, Blood-brain barrier disruption using a diagnostic ultrasound scanner and Definity® in mice, Ultrasound in Medicine and Biology, 35:1298-1308, 2009 | J Song, Y Liu, SL Gewalt, GCofer, GA Johnson, QH Liu, Least-square NUFFT methods applied to 2-D and 3-D radially encoded MR image reconstruction, IEEE Transactions on Biomedical Engineering, 56(4):1134-1142, 2009 | |
| Z Cleveland, H Moeller, L Hedlund, B Driehuys, Continuously infusing hyperpolarized 129Xe into flowing aqueous solutions using hydrophobic gas exchange membranes, J Phys Chem B, 113(37): 12489-12499, 2009. | AC Thomas, EN Potts, BT Chen, DM Slipetz, WM Foster, B Driehuys. A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized (3)He MRI, NMR Biomed. 22(5): 502-515, 2009 | |
| B Driehuys, H Moeller, J Pollaro, Z Cleveland, LW Hedlund, MRI of pulmonary perfusion and Xe gas exchange in rats by intravenous injection of hyperpolarized 129Xe, Radiology 252(2): 386-393, 2009 | X Zhang, C Badea, Effects of sampling strategy on image quality in noncontact panoramic fluorescence diffuse optical tomography for small animal imaging, Optics Express 17(7): 5125-5138, 2009 | |
| GP Howles, JC Nouls, Y Qi, GA Johnson, Rapid production of specialized animal handling devices using computer-aided design and solid freeform fabrication, JMRI 30(2):466-471, 2009. | X Zhang, C Badea, M Jacob, GA Johnson, Development of a noncontact 3-D fluorescence tomography system for small animal in vivo imaging, Proc Soc Photo Opt Instrum Eng. 7191 2009 | |
| M Lin, CT Marshall, Y Qi, SM Johnston, CT Badea, CA Piantadosi, GA Johnson, Quantitative blood flow measurements in the small animal cardiopulmonary system using digital subtraction angiography, Medical Physics 36(11): 5347-5358, 2009. | You Tube—Brain Model—(K Kernstine) Each brain structure was segmented individually using Amira 6 software http://www.youtube.com/watch?v=Svh_K75AVUw |
2009 publications in press
| E Bucholz, K Ghaghada, Y Qi, S Mukundan, HA Rockman, GA Johnson, Cardiovascular phenotyping of the mouse heart using a 4d radial acquisition and liposomal Gd-DTPA-BMA, Magnetic Resonance in Medicine | A Petiet, GA Johnson, Activing staining of mouse embryos for magnetic resonance microscopy. In: TD Hewitson, IA Darby (Eds), Histology Protocols (Methods in Molecular Biology), Springer-Humana Press, Totowa, NJ, expected January 2010. | |
| GP Howles, KB Ghaghada, Y Qi, S Mukundan, Jr., GA Johnson, High-resolution magnetic resonance angiography in the mouse using a nanoparticle blood-pool contrast agent, Magnetic Resonance in Medicine | X Zhang, CT Badea, GA Johnson, Three-dimensional reconstruction in free-space whole-body fluorescence tomography of mice using optically reconstructed surface and atlas anatomy, Journal of Biomedical Optics | |
| NN Mistry, Y Qi, LW Hedlund, GA Johnson, Ventilation/perfusion imaging in a rat model of airway obstruction, Magnetic Resonance in Medicine |
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